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No reported conflicts. Facebook Twitter Email Syndicate. As previously reported, we diagnosed possible Candida chorioretinitis, as opposed to proven or probable Candida endophthalmitis or chorioretinitis, if chorioretinal lesions occurred in patients who had alternate potential causes for their retinal abnormalities, such as diabetes mellitus, hypertension, or concomitant bacteremia [ 1 ].
Rothova was involved in data analysis and interpretation, writing the manuscript, and final approval of the version submitted for publication. Cite Citation. Probable Candida endophthalmitis was defined as vitritis or fluffy lesions with extension into the vitreous. None of the cases of Candida chorioretinitis progressed to endophthalmitis during systemic treatment, and surgical intervention or intraocular administration of antifungal drugs was not required. Cancel Continue.
It is likely that patient selection, and less advanced blood culture techniques that led to a prolonged time before detection and treatment of candidemia, may have led to a higher reported incidence of hematogenous dissemination of infection. The large randomized trials comparing echinocandins for treatment of candidemia and disseminated candidiasis [ 17—21 ] provide limited information on ocular manifestations.
Test Your Knowledge - and learn some interesting things along the way. Among all Candida species, C. Related articles in Web of Science Google Scholar. Most patients with ocular lesions found at fundoscopy did not exhibit symptoms of ocular involvement. Resources for candidemia Time Traveler! The sea, hobgoblins, and blankets. Amphotericin B was given intravenously at. Sobel, Markus Ruhnke, Peter G. Jack D.